Detail information to gene: CD40
Gene symbol
CD40
Gene description
CD40 molecule, TNF receptor superfamily member 5
Gene aliases
Bp50
CDW40
MGC9013
p50
TNFRSF5
Species
Human
Chromosomal location
20q12-q13.2
Entrez ID
958
Ensembl ID
ENSG00000101017
Molecular association
PSC
Literature
PubMed: 12790080
PubMed: 16037832
PubMed: 16448457
Further molecular associations
Functional associations to gene: CD40
RNA Seq Atlas
LoMA associations
PSC
CellMinerHCC data
GeneOntology
immune response-regulating cell surface receptor signaling pathway
transmembrane receptor activity
plasma membrane
integral to plasma membrane
protein complex assembly
apoptosis
inflammatory response
signal transduction
multicellular organismal development
external side of plasma membrane
enzyme binding
platelet activation
positive regulation of B cell proliferation
positive regulation of interleukin-12 production
B cell proliferation
positive regulation of I-kappaB kinase/NF-kappaB cascade
positive regulation of isotype switching to IgG isotypes
regulation of immune response
regulation of immunoglobulin secretion
Associated Pathways
Cytokine-cytokine receptor interaction
Cell adhesion molecules (CAMs)
Toll-like receptor signaling pathway
Asthma
Autoimmune thyroid disease
Allograft rejection