Detail information to gene: TNFRSF10A
Gene symbol TNFRSF10A
Gene description tumor necrosis factor receptor superfamily, member 10a
Gene aliases APO2
CD261
DR4
MGC9365
TRAILR1
TRAILR-1
Species Human
Chromosomal location 8p21
Entrez ID 8797
Ensembl ID ENSG00000104689
Molecular association PSC
Literature PubMed: 8276178
PubMed: 8525656
PubMed: 11394667
Further molecular associations NASH
HCC
AIH
CCC
Functional associations to gene: TNFRSF10A
RNA Seq Atlas
LoMA associations NASH
HCC
PSC
AIH
CCC
CellMinerHCC data
GeneOntology receptor activity
death receptor activity
apoptosis
induction of apoptosis
caspase activation
signal transduction
activation of NF-kappaB-inducing kinase activity
induction of apoptosis via death domain receptors
caspase activator activity
membrane
integral to membrane
TRAIL binding
Associated Pathways Cytokine-cytokine receptor interaction
Apoptosis
Natural killer cell mediated cytotoxicity