Detail information to gene: CASP8
Gene symbol	CASP8
Gene description	caspase 8, apoptosis-related cysteine peptidase
Gene aliases	ALPS2B CAP4 FLICE FLJ17672 MACH MCH5 MGC78473
Species	Human
Chromosomal location	2q33-q34
Entrez ID	841
Ensembl ID	ENSG00000064012
Molecular association	HCC
Literature	PubMed: 10025875
Further molecular associations	CCC PBC
Functional associations to gene: CASP8
RNA Seq Atlas
LoMA associations	CCC HCC PBC
CellMinerHCC data
GeneOntology	angiogenesis neural tube formation signal transducer activity protein binding nucleus cytoplasm mitochondrion cytoskeleton proteolysis heart development cysteine-type peptidase activity apoptotic program macrophage differentiation Noc1p-Noc2p complex caspase activity identical protein binding regulation of apoptosis positive regulation of I-kappaB kinase/NF-kappaB cascade
Associated Pathways	Neurodegenerative Diseases p53 signaling pathway Apoptosis Toll-like receptor signaling pathway Huntington's disease Dentatorubropallidoluysian atrophy (DRPLA)