Detail information to gene: CASP3
Gene symbol	CASP3
Gene description	caspase 3, apoptosis-related cysteine peptidase
Gene aliases	CPP32 CPP32B SCA-1
Species	Human
Chromosomal location	4q34
Entrez ID	836
Ensembl ID	ENSG00000164305
Molecular association	HCC
Literature	PubMed: 10928128
Further molecular associations
Functional associations to gene: CASP3
RNA Seq Atlas
LoMA associations	HCC
CellMinerHCC data
GeneOntology	B cell homeostasis release of cytochrome c from mitochondria cyclin-dependent protein kinase inhibitor activity protein binding cytoplasm DNA fragmentation during apoptosis proteolysis apoptosis induction of apoptosis heart development sensory perception of sound cysteine-type peptidase activity induction of apoptosis via death domain receptors induction of apoptosis by oxidative stress response to UV response to wounding keratinocyte differentiation caspase activity negative regulation of B cell proliferation T cell homeostasis cell fate commitment negative regulation of cyclin-dependent protein kinase activity negative regulation of activated T cell proliferation
Associated Pathways	Neurodegenerative Diseases MAPK signaling pathway p53 signaling pathway Apoptosis Natural killer cell mediated cytotoxicity Alzheimer's disease Huntington's disease Dentatorubropallidoluysian atrophy (DRPLA) Epithelial cell signaling in Helicobacter pylori infection Colorectal cancer