Detail information to gene: CASP1
Gene symbol CASP1
Gene description caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Gene aliases ICE
IL1BC
P45
Species Human
Chromosomal location 11q23
Entrez ID 834
Ensembl ID ENSG00000137752
Molecular association HCC
Literature PubMed: 10928128
Further molecular associations
Functional associations to gene: CASP1
RNA Seq Atlas
LoMA associations HCC
CellMinerHCC data
GeneOntology signal transducer activity
protein binding
intracellular
proteolysis
signal transduction
cysteine-type peptidase activity
caspase activator activity
caspase activity
regulation of apoptosis
positive regulation of I-kappaB kinase/NF-kappaB cascade
Associated Pathways Neurodegenerative Diseases
Huntington's disease
Dentatorubropallidoluysian atrophy (DRPLA)