Detail information to gene: BCL2
Gene symbol	BCL2
Gene description	B-cell CLL/lymphoma 2
Gene aliases	Bcl-2
Species	Human
Chromosomal location	18q21.33
Entrez ID	596
Ensembl ID	ENSG00000171791
Molecular association	HCC
Literature	PubMed: 12810626
Further molecular associations	AIH CCC Liver_Fibrosis NASH PBC
Functional associations to gene: BCL2
RNA Seq Atlas
LoMA associations	NASH HCC AIH Liver_Fibrosis PBC CCC
CellMinerHCC data
GeneOntology	release of cytochrome c from mitochondria protease binding protein binding nucleus cytoplasm mitochondrion mitochondrial outer membrane endoplasmic reticulum cytosol apoptosis anti-apoptosis humoral immune response female pregnancy response to radiation response to iron ion membrane integral to membrane nuclear membrane negative regulation of cellular pH reduction response to nicotine protein homodimerization activity negative regulation of apoptosis regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis regulation of mitochondrial membrane permeability protein heterodimerization activity neuron apoptosis BH3 domain binding defense response to virus regulation of mitochondrial membrane potential negative regulation of mitochondrial depolarization
Associated Pathways	Neurodegenerative Diseases Apoptosis Focal adhesion Amyotrophic lateral sclerosis (ALS) Colorectal cancer Prostate cancer Small cell lung cancer