Detail information to gene: BAX
Gene symbol	BAX
Gene description	BCL2-associated X protein
Gene aliases	BCL2L4
Species	Human
Chromosomal location	19q13.3-q13.4
Entrez ID	581
Ensembl ID	ENSG00000087088
Molecular association	HCC
Literature	PubMed: 12668978 PubMed: 15492826
Further molecular associations	CCC
Functional associations to gene: BAX
RNA Seq Atlas
LoMA associations	CCC HCC
CellMinerHCC data
GeneOntology	T cell homeostatic proliferation release of cytochrome c from mitochondria protein insertion into mitochondrial membrane during induction of apoptosis B cell homeostatic proliferation molecular_function protein binding cellular_component soluble fraction cytoplasm mitochondrion mitochondrial outer membrane mitochondrial permeability transition pore complex endoplasmic reticulum cytosol apoptosis induction of apoptosis caspase activation response to DNA damage stimulus cell cycle germ cell development spermatogenesis nervous system development mitochondrial fusion lipid binding induction of apoptosis by extracellular signals induction of apoptosis by intracellular signals negative regulation of survival gene product expression caspase activation via cytochrome c apoptotic mitochondrial changes response to wounding response to toxin establishment or maintenance of transmembrane electrochemical gradient membrane integral to membrane nuclear fragmentation during apoptosis mitochondrial membrane protein homodimerization activity regulation of apoptosis positive regulation of apoptosis regulation of caspase activity regulation of protein homodimerization activity regulation of protein heterodimerization activity negative regulation of neuron apoptosis cytosolic part negative regulation of cell cycle retinal cell programmed cell death pore complex protein heterodimerization activity negative regulation of fibroblast proliferation protein homooligomerization neuron apoptosis BH3 domain binding regulation of mitochondrial membrane potential Sertoli cell proliferation
Associated Pathways	Neurodegenerative Diseases p53 signaling pathway Apoptosis Amyotrophic lateral sclerosis (ALS) Colorectal cancer