Detail information to gene: BAX
Gene symbol BAX
Gene description BCL2-associated X protein
Gene aliases BCL2L4
Species Human
Chromosomal location 19q13.3-q13.4
Entrez ID 581
Ensembl ID ENSG00000087088
Molecular association HCC
Literature PubMed: 12668978
PubMed: 15492826
Further molecular associations CCC
Functional associations to gene: BAX
RNA Seq Atlas
LoMA associations CCC
HCC
CellMinerHCC data
GeneOntology T cell homeostatic proliferation
release of cytochrome c from mitochondria
protein insertion into mitochondrial membrane during induction of apoptosis
B cell homeostatic proliferation
molecular_function
protein binding
cellular_component
soluble fraction
cytoplasm
mitochondrion
mitochondrial outer membrane
mitochondrial permeability transition pore complex
endoplasmic reticulum
cytosol
apoptosis
induction of apoptosis
caspase activation
response to DNA damage stimulus
cell cycle
germ cell development
spermatogenesis
nervous system development
mitochondrial fusion
lipid binding
induction of apoptosis by extracellular signals
induction of apoptosis by intracellular signals
negative regulation of survival gene product expression
caspase activation via cytochrome c
apoptotic mitochondrial changes
response to wounding
response to toxin
establishment or maintenance of transmembrane electrochemical gradient
membrane
integral to membrane
nuclear fragmentation during apoptosis
mitochondrial membrane
protein homodimerization activity
regulation of apoptosis
positive regulation of apoptosis
regulation of caspase activity
regulation of protein homodimerization activity
regulation of protein heterodimerization activity
negative regulation of neuron apoptosis
cytosolic part
negative regulation of cell cycle
retinal cell programmed cell death
pore complex
protein heterodimerization activity
negative regulation of fibroblast proliferation
protein homooligomerization
neuron apoptosis
BH3 domain binding
regulation of mitochondrial membrane potential
Sertoli cell proliferation
Associated Pathways Neurodegenerative Diseases
p53 signaling pathway
Apoptosis
Amyotrophic lateral sclerosis (ALS)
Colorectal cancer