Detail information to gene: PTGS2
Gene symbol PTGS2
Gene description prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Gene aliases COX2
COX-2
GRIPGHS
hCox-2
PGG/HS
PGHS-2
PHS-2
Species Human
Chromosomal location 1q25.2-q25.3
Entrez ID 5743
Ensembl ID ENSG00000073756
Molecular association PSC
Literature PubMed: 11584358
PubMed: 12143054
Further molecular associations CCC
HCC
Liver_Fibrosis
Functional associations to gene: PTGS2
RNA Seq Atlas
LoMA associations CCC
HCC
Liver_Fibrosis
PSC
CellMinerHCC data
GeneOntology prostaglandin biosynthetic process
peroxidase activity
prostaglandin-endoperoxide synthase activity
iron ion binding
nucleus
cytoplasm
fatty acid biosynthetic process
cell motion
regulation of blood pressure
membrane
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
cyclooxygenase pathway
keratinocyte differentiation
anagen
metal ion binding
regulation of inflammatory response
Associated Pathways Arachidonic acid metabolism
VEGF signaling pathway
Small cell lung cancer