Detail information to gene: PTEN
Gene symbol	PTEN
Gene description	phosphatase and tensin homolog
Gene aliases	BZS MGC11227 MHAM MMAC1 PTEN1 TEP1
Species	Human
Chromosomal location	10q23.3
Entrez ID	5728
Ensembl ID
Molecular association	NASH
Literature	PubMed: 16101243 PubMed: 16214396
Further molecular associations	CCC HCC
Functional associations to gene: PTEN
RNA Seq Atlas
LoMA associations	CCC HCC NASH
CellMinerHCC data
GeneOntology	regulation of cyclin-dependent protein kinase activity phosphatidylinositol-3-phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein binding cytoplasm protein amino acid dephosphorylation lipid metabolic process induction of apoptosis cell cycle central nervous system development heart development protein tyrosine/serine/threonine phosphatase activity cell proliferation negative regulation of cell proliferation lipid binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity cell migration hydrolase activity phosphatase activity PDZ domain binding negative regulation of cell migration regulation of protein stability negative regulation of apoptosis negative regulation of cell cycle inositol phosphate dephosphorylation phosphoinositide dephosphorylation inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity negative regulation of focal adhesion formation negative regulation of protein kinase B signaling cascade
Associated Pathways	Inositol phosphate metabolism Phosphatidylinositol signaling system p53 signaling pathway Focal adhesion Tight junction Endometrial cancer Glioma Prostate cancer Melanoma Small cell lung cancer