Detail information to gene: ATM
Gene symbol ATM
Gene description ataxia telangiectasia mutated
Gene aliases TEL1
AT1
DKFZp781A0353
ATD
TELO1
ATE
MGC74674
ATDC
ATC
ATA
Species Human
Chromosomal location 11q22-q23
Entrez ID 472
Ensembl ID ENSG00000149311
Molecular association HCC
Literature PubMed: 12866955
PubMed: 15707569
Further molecular associations
Functional associations to gene: ATM
RNA Seq Atlas
LoMA associations HCC
CellMinerHCC data
GeneOntology DNA damage checkpoint
somitogenesis
DNA binding
protein serine/threonine kinase activity
nucleus
spindle
DNA repair
protein amino acid phosphorylation
cell cycle
mitotic cell cycle spindle assembly checkpoint
meiotic recombination
signal transduction
female gamete generation
brain development
heart development
DNA damage response, signal transduction resulting in induction of apoptosis
response to ionizing radiation
1-phosphatidylinositol-3-kinase activity
transferase activity
phosphotransferase activity, alcohol group as acceptor
negative regulation of cell cycle
protein N-terminus binding
Associated Pathways Cell cycle
p53 signaling pathway
Apoptosis