Detail information to gene: IL10
Gene symbol IL10
Gene description interleukin 10
Gene aliases CSIF
IL-10
IL10A
MGC126450
MGC126451
TGIF
Species Human
Chromosomal location 1q31-q32
Entrez ID 3586
Ensembl ID ENSG00000136634
Molecular association PSC
Literature PubMed: 9543183
PubMed: 10037051
Further molecular associations AIH
HCC
Liver_Fibrosis
Functional associations to gene: IL10
RNA Seq Atlas
LoMA associations AIH
HCC
Liver_Fibrosis
PSC
CellMinerHCC data
GeneOntology cytokine activity
interleukin-10 receptor binding
protein binding
extracellular region
extracellular space
anti-apoptosis
inflammatory response
immune response
cytoplasmic sequestering of NF-kappaB
cell-cell signaling
hemopoiesis
B cell differentiation
leukocyte chemotaxis
negative regulation of myeloid dendritic cell activation
negative regulation of interleukin-12 production
T-helper 2 type immune response
B cell proliferation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of nitric oxide biosynthetic process
negative regulation of interferon-gamma biosynthetic process
regulation of isotype switching
negative regulation of MHC class II biosynthetic process
positive regulation of MHC class II biosynthetic process
negative regulation of interferon-alpha biosynthetic process
Associated Pathways Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
T cell receptor signaling pathway
Asthma
Autoimmune thyroid disease
Allograft rejection