Detail information to gene: IL4
Gene symbol	IL4
Gene description	interleukin 4
Gene aliases	BCGF1 BCGF-1 BSF1 IL-4 MGC79402
Species	Human
Chromosomal location	5q31.1
Entrez ID	3565
Ensembl ID	ENSG00000113520
Molecular association	AIH
Literature	PubMed: 15301856 PubMed: 16242912
Further molecular associations	Liver_Fibrosis
Functional associations to gene: IL4
RNA Seq Atlas
LoMA associations	AIH Liver_Fibrosis
CellMinerHCC data
GeneOntology	cytokine activity interleukin-4 receptor binding protein binding extracellular region extracellular space chemotaxis cellular defense response cholesterol metabolic process B cell differentiation positive regulation of B cell proliferation T-helper 2 type immune response positive regulation of T cell proliferation positive regulation of activated T cell proliferation regulation of phosphorylation positive regulation of tyrosine phosphorylation of Stat5 protein negative regulation of apoptosis connective tissue growth factor biosynthetic process regulation of isotype switching positive regulation of MHC class II biosynthetic process negative regulation of osteoclast differentiation positive regulation of transcription from RNA polymerase II promoter positive regulation of isotype switching to IgE isotypes positive regulation of isotype switching to IgG isotypes regulation of immune response
Associated Pathways	Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Hematopoietic cell lineage T cell receptor signaling pathway Fc epsilon RI signaling pathway Asthma Autoimmune thyroid disease Allograft rejection