Detail information to gene: IL2
Gene symbol
IL2
Gene description
interleukin 2
Gene aliases
IL-2
lymphokine
TCGF
Species
Human
Chromosomal location
4q26-q27
Entrez ID
3558
Ensembl ID
ENSG00000109471
Molecular association
PSC
Literature
PubMed: 1385768
PubMed: 7590574
PubMed: 11413121
Further molecular associations
Functional associations to gene: IL2
RNA Seq Atlas
LoMA associations
PSC
CellMinerHCC data
GeneOntology
cytokine activity
interleukin-2 receptor binding
protein binding
extracellular region
extracellular space
anti-apoptosis
immune response
cell adhesion
cell-cell signaling
positive regulation of cell proliferation
kinase activator activity
natural killer cell activation
T cell differentiation
positive regulation of cell growth
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of transcription from RNA polymerase II promoter
regulation of T cell homeostatic proliferation
positive regulation of isotype switching to IgG isotypes
negative regulation of lymphocyte proliferation
negative regulation of inflammatory response
positive regulation of immunoglobulin secretion
Associated Pathways
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
T cell receptor signaling pathway
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease