Detail information to gene: FAS
Gene symbol FAS
Gene description Fas (TNF receptor superfamily, member 6)
Gene aliases ALPS1A
APO-1
APT1
CD95
FAS1
FASTM
TNFRSF6
Species Human
Chromosomal location 10q24.1
Entrez ID 355
Ensembl ID ENSG00000026103
Molecular association PBC
Literature PubMed: 9293893
PubMed: 9397977
Further molecular associations HCC
PSC
AIH
CCC
Functional associations to gene: FAS
RNA Seq Atlas
LoMA associations HCC
PSC
AIH
PBC
CCC
CellMinerHCC data
GeneOntology transmembrane receptor activity
protein binding
soluble fraction
cytosol
protein complex assembly
apoptosis
anti-apoptosis
induction of apoptosis
activated T cell apoptosis
inflammatory cell apoptosis
transformed cell apoptosis
immune response
signal transduction
induction of apoptosis via death domain receptors
external side of plasma membrane
membrane
integral to membrane
identical protein binding
regulation of apoptosis
negative thymic T cell selection
Associated Pathways MAPK signaling pathway
Cytokine-cytokine receptor interaction
p53 signaling pathway
Apoptosis
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease