Detail information to gene: APEX1
Gene symbol APEX1
Gene description APEX nuclease (multifunctional DNA repair enzyme) 1
Gene aliases APEN
APEX
APX
APE
APE-1
REF1
REF-1
APE1
HAP1
Species Human
Chromosomal location 14q11.2-q12
Entrez ID 328
Ensembl ID ENSG00000100823
Molecular association CCC
Literature PubMed: 17984110
Further molecular associations
Functional associations to gene: APEX1
RNA Seq Atlas
LoMA associations CCC
CellMinerHCC data
GeneOntology magnesium ion binding
DNA binding
transcription coactivator activity
transcription corepressor activity
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
ribonuclease H activity
phosphodiesterase I activity
uracil DNA N-glycosylase activity
protein binding
nucleus
cytoplasm
endoplasmic reticulum
ribosome
base-excision repair
transcription from RNA polymerase II promoter
3'-5' exonuclease activity
oxidoreductase activity
lyase activity
perinuclear region of cytoplasm
regulation of DNA binding
Associated Pathways Base excision repair