Detail information to gene: EGFR
Gene symbol	EGFR
Gene description	epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene aliases	ERBB ERBB1 HER1 mENA PIG61
Species	Human
Chromosomal location	7p12
Entrez ID	1956
Ensembl ID	ENSG00000146648
Molecular association	CCC
Literature	PubMed: 11261824 PubMed: 12143054 PubMed: 12360423 PubMed: 12438243 PubMed: 15213623 PubMed: 15665568 PubMed: 15833824 PubMed: 15855163 PubMed: 15921858 PubMed: 16032426 PubMed: 16116640 PubMed: 16551849 PubMed: 16790433 PubMed: 16984600 PubMed: 17079474
Further molecular associations	PSC
Functional associations to gene: EGFR
RNA Seq Atlas
LoMA associations	PSC CCC
CellMinerHCC data
GeneOntology	nucleotide binding ossification double-stranded DNA binding MAP/ERK kinase kinase activity transmembrane receptor activity epidermal growth factor receptor activity protein binding ATP binding extracellular space intracellular nucleus cytoplasm endosome plasma membrane response to stress cell cycle signal transduction cell surface receptor linked signal transduction epidermal growth factor receptor signaling pathway activation of phospholipase C activity cell proliferation positive regulation of cell proliferation integral to membrane kinase activity basolateral plasma membrane cell-cell adhesion transferase activity AP-2 adaptor complex endocytic vesicle nitric-oxide synthase regulator activity positive regulation of cell migration positive regulation of phosphorylation identical protein binding calcium-dependent phospholipase A2 activation positive regulation of MAP kinase activity positive regulation of nitric oxide biosynthetic process negative regulation of cell cycle protein amino acid autophosphorylation protein heterodimerization activity positive regulation of epithelial cell proliferation regulation of peptidyl-tyrosine phosphorylation regulation of nitric-oxide synthase activity actin filament binding protein insertion into membrane
Associated Pathways	MAPK signaling pathway ErbB signaling pathway Calcium signaling pathway Cytokine-cytokine receptor interaction Dorso-ventral axis formation Focal adhesion Adherens junction Gap junction Regulation of actin cytoskeleton GnRH signaling pathway Epithelial cell signaling in Helicobacter pylori infection Colorectal cancer Pancreatic cancer Endometrial cancer Glioma Prostate cancer Melanoma Bladder cancer Non-small cell lung cancer