Detail information to gene: AKR1C1
Gene symbol AKR1C1
Gene description aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Gene aliases MGC8954
DD1
2-ALPHA-HSD
DDH1
DDH
C9
MBAB
20-ALPHA-HSD
H-37
HAKRC
Species Human
Chromosomal location 10p15-p14
Entrez ID 1645
Ensembl ID ENSG00000187134
Molecular association HCC
Literature PubMed: 7476889
PubMed: 9973208
PubMed: 12579257
Further molecular associations
Functional associations to gene: AKR1C1
RNA Seq Atlas
LoMA associations HCC
CellMinerHCC data
GeneOntology aldo-keto reductase activity
cytosol
electron transport
xenobiotic metabolic process
digestion
bile acid metabolic process
bile acid and bile salt transport
oxidoreductase activity
cholesterol absorption
bile acid binding
cholesterol homeostasis
20-alpha-hydroxysteroid dehydrogenase activity
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
protein homooligomerization
Associated Pathways Metabolism of xenobiotics by cytochrome P450