Detail information to gene: CYP3A4
Gene symbol
CYP3A4
Gene description
cytochrome P450, family 3, subfamily A, polypeptide 4
Gene aliases
HLP
P450PCN1
CYP3A
CYP3A3
CP33
P450C3
MGC126680
CP34
NF-25
Species
Human
Chromosomal location
7q21.1
Entrez ID
1576
Ensembl ID
ENSG00000160868
Molecular association
Liver_Fibrosis
Literature
PubMed: 11786960
Further molecular associations
HCC
Functional associations to gene: CYP3A4
RNA Seq Atlas
LoMA associations
HCC
Liver_Fibrosis
CellMinerHCC data
GeneOntology
iron ion binding
membrane fraction
endoplasmic reticulum
microsome
electron transport
lipid metabolic process
xenobiotic metabolic process
cell surface
membrane
integral to membrane
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
metal ion binding
unspecific monooxygenase activity
quinine 3-monooxygenase activity
Associated Pathways
gamma-Hexachlorocyclohexane degradation
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes