Detail information to gene: CYP3A4
Gene symbol CYP3A4
Gene description cytochrome P450, family 3, subfamily A, polypeptide 4
Gene aliases HLP
P450PCN1
CYP3A
CYP3A3
CP33
P450C3
MGC126680
CP34
NF-25
Species Human
Chromosomal location 7q21.1
Entrez ID 1576
Ensembl ID ENSG00000160868
Molecular association Liver_Fibrosis
Literature PubMed: 11786960
Further molecular associations HCC
Functional associations to gene: CYP3A4
RNA Seq Atlas
LoMA associations HCC
Liver_Fibrosis
CellMinerHCC data
GeneOntology iron ion binding
membrane fraction
endoplasmic reticulum
microsome
electron transport
lipid metabolic process
xenobiotic metabolic process
cell surface
membrane
integral to membrane
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
metal ion binding
unspecific monooxygenase activity
quinine 3-monooxygenase activity
Associated Pathways gamma-Hexachlorocyclohexane degradation
Linoleic acid metabolism
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes