Detail information to gene: CDKN2A
Gene symbol CDKN2A
Gene description cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
Gene aliases MTS1
CMM2
p14ARF
TP16
p19
INK4
CDKN2
p16
CDK4I
p16INK4
p14
p16INK4a
MLM
INK4a
ARF
Species Human
Chromosomal location 9p21
Entrez ID 1029
Ensembl ID ENSG00000147889
Molecular association CCC
Literature PubMed: 7796400
PubMed: 10334895
PubMed: 10718212
PubMed: 10769677
PubMed: 11034592
PubMed: 11100316
PubMed: 11340376
PubMed: 11836554
PubMed: 12107841
PubMed: 12210082
PubMed: 12213730
PubMed: 12360471
PubMed: 12378511
PubMed: 12668978
PubMed: 12738733
PubMed: 14647920
PubMed: 15014024
PubMed: 15467712
PubMed: 15471559
PubMed: 15619210
PubMed: 15915369
PubMed: 16373701
Further molecular associations HCC
PSC
Liver_Fibrosis
PBC
Functional associations to gene: CDKN2A
RNA Seq Atlas
LoMA associations HCC
PSC
Liver_Fibrosis
PBC
CCC
CellMinerHCC data
GeneOntology cell cycle checkpoint
regulation of cyclin-dependent protein kinase activity
DNA binding
cyclin-dependent protein kinase inhibitor activity
protein binding
cellular_component
nucleus
nucleoplasm
nucleolus
cytoplasm
transcription
regulation of transcription, DNA-dependent
rRNA processing
apoptosis
cell cycle
cell cycle arrest
aging
cell aging
negative regulation of cell proliferation
epidermis development
negative regulation of cyclin-dependent protein kinase activity
Associated Pathways Cell cycle
p53 signaling pathway
Pancreatic cancer
Glioma
Melanoma
Bladder cancer
Chronic myeloid leukemia
Non-small cell lung cancer