Detail information to gene: CDKN1A
Gene symbol
CDKN1A
Gene description
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Gene aliases
CAP20
CDKN1
CIP1
MDA-6
P21
p21CIP1
SDI1
WAF1
Species
Human
Chromosomal location
6p21.2
Entrez ID
1026
Ensembl ID
ENSG00000124762
Molecular association
CCC
Literature
PubMed: 10799743
PubMed: 11124819
PubMed: 12829999
Further molecular associations
HCC
PBC
Functional associations to gene: CDKN1A
RNA Seq Atlas
LoMA associations
CCC
HCC
PBC
CellMinerHCC data
GeneOntology
regulation of cyclin-dependent protein kinase activity
cyclin-dependent protein kinase holoenzyme complex
protein kinase activity
cyclin-dependent protein kinase inhibitor activity
protein binding
nucleus
cytosol
response to DNA damage stimulus
cell cycle
cell cycle arrest
zinc ion binding
negative regulation of cell proliferation
induction of apoptosis by intracellular signals
response to UV
kinase activity
cyclin binding
positive regulation of B cell proliferation
negative regulation of apoptosis
positive regulation of non-apoptotic programmed cell death
negative regulation of cyclin-dependent protein kinase activity
metal ion binding
Associated Pathways
ErbB signaling pathway
Cell cycle
p53 signaling pathway
Glioma
Prostate cancer
Melanoma
Bladder cancer
Chronic myeloid leukemia