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CellMinerHCC
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Details to gene: PSEN1
Detail inforamtion to gene: PSEN1
Gene symbol
PSEN1
Gene description
presenilin 1
Type
protein-coding
Gene aliases
AD3
FAD
PS1
S182
Species
Human
Chromosomal location
14q24.3
External Data
Entrez Gene:5663
EnsEMBL:ENSG00000080815
HGNC:9508
HPRD:00087
OMIM:104311
BioGPS
Nextbio
GENT
Functional associations to gene: PSEN1
LoMA associations
nothing found
RNA Seq - Normal Tissues
Microarray - BioGPS Normal Tissues
Microarray - NCI60 Tumor Celllines
Microarray - CellNavigator
Tissues FRMA Z-Score
Tissues M-Values
Disease FRMA Z-Score
Disease M-Values
Microarray - CellMinerHCC
GeneOntology
kinetochore
blood vessel development
cell fate specification
neuron migration
endopeptidase activity
protein binding
intracellular
membrane fraction
nucleus
integral to nuclear inner membrane
mitochondrion
endoplasmic reticulum
Golgi apparatus
integral to plasma membrane
membrane protein ectodomain proteolysis
cellular calcium ion homeostasis
apoptosis
anti-apoptosis
chromosome segregation
cell adhesion
Notch receptor processing
intracellular signaling cascade
heart development
memory
membrane
protein processing
embryonic limb morphogenesis
axon
dendrite
cytoplasmic vesicle
ciliary rootlet
regulation of phosphorylation
anagen
amyloid precursor protein catabolic process
cell soma
positive regulation of apoptosis
positive regulation of catalytic activity
positive regulation of protein kinase activity
smooth endoplasmic reticulum calcium ion homeostasis
Associated Pathways
Neurodegenerative Diseases
Wnt signaling pathway
Notch signaling pathway
Alzheimer's disease