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Details to gene: ADRB2
Detail inforamtion to gene: ADRB2
Gene symbol
ADRB2
Gene description
adrenergic, beta-2-, receptor, surface
Type
protein-coding
Gene aliases
ADRB2R
ADRBR
B2AR
BAR
BETA2AR
Species
Human
Chromosomal location
5q31-q32
External Data
Entrez Gene:154
EnsEMBL:ENSG00000169252
HGNC:286
HPRD:00187
OMIM:109690
BioGPS
Nextbio
GENT
Functional associations to gene: ADRB2
LoMA associations
NASH
RNA Seq - Normal Tissues
Microarray - BioGPS Normal Tissues
Microarray - NCI60 Tumor Celllines
Microarray - CellNavigator
Tissues FRMA Z-Score
Tissues M-Values
Disease FRMA Z-Score
Disease M-Values
Microarray - CellMinerHCC
GeneOntology
activation of MAPK activity
rhodopsin-like receptor activity
regulation of systemic arterial blood pressure by norepinephrine-epinephrine
diet induced thermogenesis
vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
regulation of sodium ion transport
desensitization of G-protein coupled receptor protein signaling pathway by arrestin
receptor activity
beta2-adrenergic receptor activity
protein binding
membrane fraction
nucleus
lysosome
endosome
plasma membrane
integral to plasma membrane
receptor-mediated endocytosis
activation of transmembrane receptor protein tyrosine kinase activity
G-protein coupled receptor protein signaling pathway
G-protein signaling, adenylate cyclase activating pathway
activation of adenylate cyclase activity
protein kinase cascade
endosome to lysosome transport
response to cold
apical plasma membrane
positive regulation of bone mineralization
heat generation
negative regulation of multicellular organism growth
protein homodimerization activity
receptor complex
positive regulation of MAPKKK cascade
bone resorption
positive regulation of transcription from RNA polymerase II promoter
negative regulation of smooth muscle contraction
brown fat cell differentiation
norepinephrine binding
Associated Pathways
Calcium signaling pathway
Neuroactive ligand-receptor interaction