Detail information to gene: APEX1
Gene symbol APEX1
Gene description APEX nuclease (multifunctional DNA repair enzyme) 1
Gene aliases HAP1
APEX
REF1
APX
REF-1
APEN
APE1
APE-1
APE
Species Human
Chromosomal location 14q11.2-q12
Entrez ID 328
Ensembl ID ENSG00000100823
Molecular association CCC
Literature PubMed: 17984110
Further molecular associations
Functional associations to gene: APEX1
RNA Seq Atlas
LoMA associations CCC
CellMinerHCC data
GeneOntology endoplasmic reticulum
cytoplasm
endodeoxyribonuclease activity
transcription from RNA polymerase II promoter
oxidoreductase activity
DNA-(apurinic or apyrimidinic site) lyase activity
phosphodiesterase I activity
nucleus
magnesium ion binding
transcription coactivator activity
ribosome
lyase activity
perinuclear region of cytoplasm
DNA binding
protein binding
ribonuclease H activity
base-excision repair
uracil DNA N-glycosylase activity
transcription corepressor activity
regulation of DNA binding
3'-5' exonuclease activity
Associated Pathways Base excision repair