Detail information to gene: AKR1C1
Gene symbol AKR1C1
Gene description aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Gene aliases MBAB
20-ALPHA-HSD
HAKRC
C9
DDH
DD1
MGC8954
DDH1
H-37
2-ALPHA-HSD
Species Human
Chromosomal location 10p15-p14
Entrez ID 1645
Ensembl ID ENSG00000187134
Molecular association HCC
Literature PubMed: 9973208
PubMed: 7476889
PubMed: 12579257
Further molecular associations
Functional associations to gene: AKR1C1
RNA Seq Atlas
LoMA associations HCC
CellMinerHCC data
GeneOntology cytosol
digestion
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
electron transport
xenobiotic metabolic process
bile acid and bile salt transport
oxidoreductase activity
20-alpha-hydroxysteroid dehydrogenase activity
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity
cholesterol homeostasis
bile acid metabolic process
protein homooligomerization
cholesterol absorption
aldo-keto reductase activity
bile acid binding
Associated Pathways Metabolism of xenobiotics by cytochrome P450